COTTON DUST: PROCEEDINGS--11TH COTTON DUST RESEARCH CONFERENCE 1987
Jan. 5-8, Dallas, TX
Editors
C. Paul Dugger & Debbie A. Richter

TABLE OF CONTENTS



SUMMARY OF THE 1987 CONFERENCE ON COTTON DUST RESEARCH

Summary of the 1987 Conference on Cotton Dust Research
Robert R. Jacobs
1


PART 1: EPIDEMIOLOGY AND HUMAN STUDIES

Acute and Chronic Byssinosis
W.S. Lynn and D.S. Lynn
3
Further Observations on Byssinotics Diagnosed in Great Britain
G.B. Rooke, A.N. Dempsey, V.F. Hiller, and J. Jacobs
5
Effects after Acute and Chronic Exposure to Cotton Dust: Summary of the Manchester Criteria
R. Rylander, R.S.F. Schilling, C.A.C. Pickering, G.B. Rooke, R.R. Jacobs, and A.N. Dempsey
9
Effects of Drug Intervention on Symptoms in the Byssinosis Syndrome
R. Rylander
10
Airway Hyperactivity and Bronchoconstriction after Inhalation of Cell-Bound Endotoxin
B. Bake, R. Rylander, and J. Fischer
12


PART 2: MICROBIOLOGY/ENDOTOXIN

Bacterial Counts on Commercial Cotton Fiber Samples from the U.S. Crop of 1985
P.B. Marsh and M.E. Simpson
15
Bacterial Counts on Cotton Fiber Field-Weathered at Five Locations in 1985
M.E. Simpson and P.B. Marsh, and T.W. Culp
18
Microbial Tightlock as a Source of Endotoxin in Cotton Dust
P.D. Millner, H.H. Perkins, Jr., and M. Kinoshita
21
Bacterial Counts on Fiber of Five Cotton Varieties Field-Weathered at Stoneville, Mississippi
M.E. Simpson, P.B. Marsh, S.T. Rayburn, Jr., and E.P. Columbus
24
The Influence of Leaf and Bract Shape and Insect Resistance Traits on Bacterial and Endotoxin Content of Cotton Fiber
Patricia D. Millner and Jack E. Jones
26
Preliminary Observations on Effects of Morphological Characters and Bacterial Blight Resistance of Cotton Plants on Bacterial Populations of Raw Cotton Fiber
Alois A. Bell, Michael D. Thomas, and Katherine M. Bell
28
A Test of Varietal and Environmental/Locational Effects on the Growth of Bacteria on Cotton Fiber Field-Weathered near College Station, Texas
M.E. Simpson, P.B. Marsh, and J.M. Halloin
32
Effect of Pain on the Microorganisms in Cotton
J.J. Fischer and P.E. Sasser
34
A Morphometric Comparison of Lungs after Aerosol Exposures to Either Aqueous Endotoxin (LPS) Suspensions or Cotton Dust
Robert Burrell and R. Clark Lantz
36
Effect of Endotoxin-Induced Mediator Release on Airway Epithelium
M.M. Cloutier and R. Thrall
39
Anti-Lung Cancer Properties of Aerosolized Endotoxin in a Mouse Model
John H. Langel, Jan L. Sykoral, Dietrich A. Weyell, and Aurelia M.C. Koros
42
Immune Response to a Lipopolysaccharide Polymyxin-B Complex
L.K. Ryan and M.H. Karol
45
A Mouse Model for Testing Biological Activity of Endotoxin Preparations
Janet J. Fischer and Charles Pfaff
47


PART 3: ETIOLOGY AND PATHOGENESIS

Cellular Responses to Cotton Dust
James A. Russell
50
Pharmacological Modification of the Airways Response to Inhaled Dust Extract in the Guinea Pig
D.A. Johnson and P.J. Nicholls Welsh
53
The Effect of Cotton Dust and Bract Extract on the Perfused Guinea Pig Lung
N. El-Mahdy and P.J. Nicholls
57
Effect of Cotton Dust and Oxo Fatty Acids on Lipid and Calcium Metabolism of Cultured Inflammatory Cell Lines
W.S. Lynn, A. Tweedale, C. Sacks, D.G. Lynn, and M. Cloyd
62
Identification and Quantitation of Alterations in the Cellular Lipid Pool by Fast Atom Bombardment Mass Spectrometry: Implications for Byssinosis
Timothy M. Logan, Kathleen M. Hess, William S. Lynn, Joyce Barclay, and David O. Lynn
66
Tannin Dependent Cellular Activation of Alveolar Macrophages
S.L. Hempel and M.S. Rohrbach
71


PART 4: ANIMAL MODEL STUDIES

A System for Exposing Laboratory Animals to Cotton Dust Aerosol That Is Stabilized with Feedback Control
D.G. Frazer, V. Robinson, D.S. DeLong, D. Rose, J. Tucker, K.C. Weber, S.A. Olenchock, and K. Jayaraman
74
Time Course of Pulmonary Response to Inhalation of Cotton Dust in Guinea Pigs and Rats
V. Castranova, V.A. Robinson, J.H. Tucker, D. Schwegler, D.A. Rose, D.S. DeLong, and D.G. Frazer
79
Relationship of the Respiratory Potencies of Cotton Dusts to Their Content of Enterobacter Agglomerans and Pseudomonas Syringae
A. Ogundiran, C. Gatty, K. Spear, I. Vyas, M. Karol, and J.J. Fischer
84
Acute Respiratory Response of Guinea Pigs to Endotoxin from Enterobacter Agglomerans, Pseudomonas Syringae and Escherichia Coli
Carolyn Gatty, Kathryn Spear, Adeniyi Ogundiran, Ivy Vyas and Meryl Karol
87
Characterization of Immunologic in Cotton Dust
Nurudeen S. Olaniran and Meryl H. Karol
89
An Animal Modification for Evaluating Epidemiological Evidence of Anti-Lung Cancer Activity of Aerosolized Cotton Dust
John H. Lange, J.L. Sykora, Dietrich A. Weyel, Georg Keleti and Evelyn E. Talbott
93
Caducous Bract Cotton
B. Muramoto, R.A. Sherman, and C.A. Ledbetter
97


PART 5: COTTON DUST: CONTROL AND DETOXIFICATION

Effects of Additives on Particle Size Distribution and Microbiology of Card Generated Cotton Dust
H.H. Perkins, Jr., R.E. Harrison, and M. Kinoshita
99
Comparative High-Performance Liquid Chromatographic Analysis of Cotton Dusts Prepared with and Without Nickel Sieve Treatment
John P. McCormick and Terrance D. Hubert
102
Endotoxin Reduction in Cotton Dust/Fiber. Part 1. Solvent Systems Survey
L.N. Domelsmith and M.A. Rousselle
105
Endotoxin Reduction in Cotton Dust/Fiber. Part 2. Extension of Dust Survey Results to Lint and Sliver.
Marie-Alice Rousselle and Linda N. Domelsmith
109
Analysis of Detoxified Cotton Dust for Endotoxin by HPLC
Nancy M. Morris, Ralph Berni, and Edwin A. Catalano
112
Use of the Guinea Pig Animal Model to Assess Treatments of Cotton Dust
M.H. Karol, A. Ogundiran, C. Gatty Patricia Millner, L.N. Domelsmith, and M.A. Rousselle
116

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