The results of 2-year field study to compare the efficacy of 4 IGR/insecticide mixtures with 4 synthetic pyrethroids against spiny bollworm, Earias insulana (Boisd.), pink bollworm, Pectinophora gossypiella (Saund.), and cotton seed bug, Oxycarenus hyalinipennis Costa revealed that, of the 4 pyrethroids tested, Bestox and Fenval provided the greatest control of cotton bollworms. Cotton yields of both treatments were also greater, with Bestox treated plats, previously treated in early season with Confider, giving the highest yield. Mavrik proved to be the least effective pyrethroid in this respect. With the exception of Mavrik, pyrethroids alone were more effective against cotton bollworms than IGR/insecticide mixtures. Deneet, a combination of methomyl and diflubenzuron, was the most effective mixture, while Delfos-2 (chlopyrifosethyl plus hexaflumuron) was ineffective with respect to control of both species of cotton bollworms and cotton yield. All of the tested insecticides significantly reduced the population density of cotton seed bug to below levels measured in the check.