In two years of field evaluation against early season boll weevils, the biorational mycoattracticide, Naturalis, which contains the entomopathogenic fungus, Beauveria bassiana, was found to be highly pathogenic to adults and effective for early season cotton protection. This material acts as an attracticide for overwintered adults and contains a feeding substrate upon which the adults feed. Laboratory bioassays also show activity against the cotton fleahopper and the whitefly. Evaluation of its efficacy in the field was determined by removal of insect samples from treated and untreated plots and by evaluation of the cotton yield as determined by fruit load and retention, and final lint production. In the history of cotton insect control, this represents the FIRST biorational approach developed for boll weevil control, and is the beginning of a new strategy for cotton insect management. Biologicals may be solely utilized in production areas where the boll weevil is the major pest, as well as in sensitive, environmental areas where pesticides cannot be used. The utilization of such a biorational should not disturb the ecological balance in early season cotton as pesticides do, and should allow greater flexibility in late season insect control strategies.