The effect of Vydate C-LV applied to cotton as two post-plant foliar applications was evaluated in field plots in 1995 and 1996. Plots were established in fields infected by Rotylenchulus reniformis in Jefferson County, AR, in 1995 and in a field infested by R. reniformis and a second field infested by Meloidogyne incognita (race 3) in 1996. Sequential foliar applications of Vydate C-LV (4.0 oz/a) at two different timing regimes (pinhead square + 10 days or second true leaf fully expanded + 10 days) in conjunction with in-furrow application of Temik 15 G (3.5 lb/a) were compared with application of Temik alone in 1995. In 1996, sequential foliar applications of Vydate C-LV at 4.0 oz/a (pinhead square + 7 days and second true leaf fully expanded + 7 days) were studied in conjunction with either in-furrow application of Temik 15 G (3.5 lb/a) or Gaucho applied as a seed treatment (8 oz/cwt seed). Application of Vydate C-LV did not result in increases in lint yield, final plant height, or position of the first fruiting node in any of the experiments. Vydate C-LV applications did, however, result in considerably slower early season increase in the population densities of both R. reniformis and M. incognita in 1996. Final nematode population densities were not significantly affected by Vydate C-LV.