The use of blending to reduce the bacterial and endotoxin content of dust was studied. A low middling (grade 51) cotton from the Memphis area was the base cotton that was blended with a scoured and bleached cotton. Five levels of the unwashed cotton were carded, 100, 75, 50, 25, 0% and fiber, dust and air were assayed. Bacterial and endotoxin levels on fiber and in air and vertical eluriated dust were reduced approximately by the dilution indicated from the blend ratio.