Multiple year studies were conducted in Tallahatchie County, Mississippi on a Dundee silt loam (Aeric ochraqualf), to evaluate the response of cotton to deep band placement of suspension lime and dry agricultural lime. The lime was applied from 20 to 40 cm deep (8 to 15 in), into the subsoil acidic zone, to raise the pH and alter the chemical barrier to root penetration and proliferation. Liming materials were applied behind a parabolic super chisel shank equipped with rolling disk hippers. This arrangement facilitated a one-pass operation to combine subsoiling, lime application, and hipping (bed formation). The subsoil liming has proved effective in raising the pH in the application zone when either dry or suspension lime was applied. Increases in seed cotton yields have been as high as 460 kg/ha (410 lbs/A) with the greatest advantages realized in dry years when the rooting depth is thought to be the greatest. In wet years, the response was less since the roots were concentrated in the upper soil profile, above the acidic zones. Ripper hipping of these soils containing acidic zones in the subsoil, without the application of lime, resulted in decreased yields in at least one year. The reduction in yield can probably be attributed to disturbing the acidic zone, allowing for greater root exposure to the acidity that is present and actually bringing the acid subsoil upward in the soil profile.