Many cotton fields have substantial variability in vegetative growth. Some areas of the field may require vegetative growth control, while other significant areas of the field have smaller stressed plants. In nine variable growth fields the retention of the bottom five first fruiting positions was directly proportional to plant height. Small, medium and large plants averaged 86, 73, and 55 percent retention of the bottom five first fruiting positions, respectively. Variable rates of Pix, plant growth regulator, were applied to different groups of cotton plants depending on plant height. The taller the plant, the higher the Pix rate. Two variable Pix treatments in 1992 and three in 1993 were compared to two uniform Pix treatments and a control with no Pix. Across nine locations for a total of 48 replications, the uniform broadcast ½ pint per acre treatment was more effective than the variable rates of Pix. Even though these were extremely variable fields the ½ pint per acre uniform rate gave an economic yield increase of 27 pounds of cotton lint per acre.