The bollworm/budworm complex (BW/TBW) constitutes a major obstacle to profitable cotton production in the Mississippi Delta. Genetic resistance in cotton to BW/TBW has the potential to aid in BW/TBW control, but the level of resistance available in conventionally bred strains does not generally provide adequate control. This study was conducted to evaluate the effectiveness of host plant resistance in combination with selected insecticide use strategies for BW/TBW control. Tests were planted at the Dean Lee Research Station (DLRS) in Alexandria and the Northeast Research.Station (NERS) in Winnsboro, Louisiana. Genotypes included La. HG-660, LA 850082, LA 870210 and 'Deltapine 511. Insecticide treatments included Karate (Lambda-cyhalothrin) at two rates; full-rate (0.032 lb AI/acre), and half-rate (0.016 lb AI/acre) as well as an untreated control. insecticide treatments were applied to all plots when larvae were present in 5% of terminals in DFL 51 + Karate at the full-rate. Averaged over six dates and all genotypes at NERS, percent BW/TBW - damaged fruit was highest (8.5%) in untreated plots, and not significantly different in plots receiving half (6.9%) vs. full (5.0%) rates. Averaged over all insecticide treatments, DPL 51 had significantly more damaged fruit (8.7%) than the other genotypes. Genotype x insecticide treatment interaction was not significant. No treatment effects on lint yield were observed at NERS. Averaged over ten dates and all genotypes at DLRS, percent BW/TBW - damaged fruit was highest (7.9%) in untreated plots, and not significantly different in plots receiving half (3.2%) vs. full (2.2%) rates. Averaged over all insecticide treatments, DPL 51 had significantly more damage (6.2%) than the other genotypes. Genotype x insecticide treatment interaction was significant, with DPL 51 suffering more damage with reduced insecticide treatments than did the other genotypes. Treatment effects on lint yield at DLRS were similar to effects on % BW/TBW - damaged fruit. In most cases, the effects of plant resistance and chemical control were additive; less insecticide was required to obtain a given level of BW/TBW control in resistance vs. susceptible genotypes.