A greenhouse experiment was conducted to determine the effectiveness of seed treatments on growth of Del-Max cotton and on plant parasitic nematodes. Seed treatments with acephate (orthene at 8 oz/cwt) or with the experimental nematicide Gus 80502 (6 and 8 oz/cwt) reduced soil populations of Tylenchorhynchus claytoni and of Paratrichodorus christiei but had no effect on those of Helicotylenchus dihystera or Hoplolaimus galeatus. The orthene treatment had no effect on root populations of Pratylenchus brachyurus, T. claytoni, or H. galeatus but the Gus 80502 treatments reduced drastically populations of all these nematodes in the root system. Orthene and Gus 80502 treatments reduced numbers of H. dihystera in the roots. The treatments had no effect on shoot height or fresh root weights; however, both rates of Gus 80502 resulted in slight reductions in fresh shoot weights.