Pix, a plant growth regulator, was applied to cotton on three farm trials to evaluate possible effects on fruiting patterns and yield. Pix was applied in multiple applications consisting of 1) 4 applications of 4 ozs. per acre 2) 2 applications of 8 ozs. per acre 3) 2 applications of 4 ozs. per acre followed by 1 application of 8 ozs. per acre 4) an untreated check treatment. Plant mapping data and yields were obtained to determine the effects of the different treatments. Regardless of treatment any Pix application reduced height and the number of sympodia over the check treatment. Trends existed at all locations related to increased boll retention in both the 1st and 2nd positions and an increase in early boll retention. While consistent trends existed, significant differences only occurred in a couple of instances. These differences were observed over all locations in favor of the Pix treatment over the check treatment regardless of the rate of Pix. Significant differences in plant mapping and yields were erratic and conclusions were difficult to make, however trends did exist in favor of the Pix applications but more work is needed to develop a sound understanding of the effects of Pix on the cotton plant.