Seed from cotton defoliation studies at the Delta Branch Experiment Station, Stoneville, MS. in 1987 and 1988 were evaluated for standard germination and physiology quality. Chemicals were applied at 20%, 40%, 60% and 80% open bolls both years. Treatments were, no defoliant, DEF, Dropp, Prep, DEF plus Prep,, Dropp plus Prep. Although there were significant differences in seed germination among treatments there was no clear pattern related to chemical(s) or percent open bolls for initial germination 1987 & 1988 and after storage at 30 C - 75% RH for 6 months in 1987. There were no significant differences among treatments for cool germination (18 C -7 days) of acid delinted seed in 1988