Preliminary experiments directed towards a practical, economical treatment to detoxify bacterial endotoxins on cotton lint are described. Effects of ammonia and gaseous aliphatic amines on endotoxins (LAL values) were measured using a flow-through system at ambient and elevated temperatures. A flowing air system was used as a control. Air and ammonia at ambient temperature had little effect on LAL values, while the volatile amines increased the values. At 100 C, air, ammonia, and all the amines decreased the LAL values. Effects of temperatures from ambient to 150 C on air and ammonia treatments were measured. Possible causes of the effects are discussed.