Various insecticides and insecticide combinations were evaluated for their ovicidal activity against Heliothis virescens (F.) eggs on cotton in laboratory and field tests. Thiodicarb and cypermethrin at rates used for control of Heliothis larvae (0.67 and 0.07 kg [AI]/ha) had the best residual activity, while profenofos used at a larval rate (1.12 kg [AI]/ha) had the best ovicidal activity when sprayed directly on eggs on foliage. Combinations of chlordimeform (0.14 kg [AI]/ha) and thiodicarb (0.14 and 0.23 kg [AI]/ha) with cypermethrin or profenofos at larval rates (0.07 and 1.12 kg [AI]/ha) produced higher egg mortalities than any of the 4 insecticides used alone. All combination treatments had significantly higher egg mortality than egg mortality obtained with chlordimeform (0.14 kg [AI]/ha) when sprayed directly on eggs and in residual activity for up to 48 h after treatment. The profenofos + thiodicarb (1.12 + 0.23 kg [AI]/ha) treatment had the best residual activity of any treatment tested. Egg mortality obtained with fenoxycarb was as good as egg mortality obtained with chlordimeform. These results demonstrate that several insecticides or insecticide combinations have good ovicidial activity against Heliothis eggs under laboratory test conditions. This activity should be confirmed in field tests.