Tarnished plant bugs and stink bugs have become key pests of cotton in the Mississippi Delta. In 2001, remote sensing technologies and site-specific management techniques were investigated for use in detection and control of these cotton pests in experimental and farm fields. In mid June, tarnished plant bug (TPB), numbers were greater in vigorously growing field zones with higher normalized difference vegetation index (NDVI) values than TPB numbers in slower growing zones with lower NDVI values. TPB occurred at or above economic threshold levels in 73%-80% of vigorously growing zones, and in 0%-16% of slower growing zones in mid June. The data indicate a potential preference by TPB for vigorous plant zones. Imagery-based prescription spray maps were created for each field and site-specific applications were made in mid June that reduced applications of insecticide by approximately 25%-35%. In July, site-specific applications were applied again for TPB control in both fields saving approximately 20%-25% of insecticide applications. In late season, NDVI values and TPB numbers were lower in early maturing zones that had reached cutout or node-above-white-flower (NAWF) = 5 + 350 heat units (DD60s). In early August, an imagery based prescription application map was created that terminated insecticide use in cutout zones in a farm field, thus saving approximately 20% of an insecticide application. In mid August, stink bugs reached threshold levels at sites that had grown rapidly in late season. An imagery based prescription spray map was generated which effectively controlled stink bugs, saving approximately 50% of an insecticide application.