Research was conducted at two locations in North Carolina investigating the use of Roundup Ready cotton for no-till (Goldsboro) and conventional-tillage cotton production (Clayton and Goldsboro). The cover crop was terminated with 1.0 lb ai/ac of Roundup Ultra approximately 2 weeks before planting. The formulation of Roundup was used was Roundup Ultra and no additional surfactants or additives were used with these treatments. Staple was applied with a nonionic surfactant at 0.25% of the spray volume.