Field experiments were conducted in 1996 at the Upper Coastal Plain Research Station in Edgecombe County, NC and the Cherry Farm in Wayne County, NC to evaluate the morphological and yield effects of postemergence (POST) applications of Roundup (Glyphosate) in Roundup-Ready^TM cotton (Gossypium hirsutum L.). Current varieties of Roundup-Ready^TM cotton exhibit a negative response to applications of Roundup when applied POST after the 4-leaf stage. The exact morphological response to these applications has not yet been determined.