Staple will provide good to excellent (80 to 100%) postemergence control of most broadleaf weeds in cotton, and will suppress yellow nutsedge and purple nutsedge However, postemergence control of sicklepod and tropic croton is generally poor. Staple also has good residual activity on some broadleaf weeds. Buctril will provide good to excellent postemergence control of most broadleaf weeds in BXN™ cotton. However, in South Carolina Buctril has not controlled sicklepod, and generally has provided poor control of Palmer amaranth. Buctril has no residual activity. Weed management in Roundup Ready™ cotton with Roundup has been evaluated only in 1995. Roundup controls a broad spectrum of weeds including grass and broadleaf species. In South Carolina, all weed management programs utilizing these new technologies have weaknesses. Therefore, we feel a residual herbicide(s)and multiple postemergence herbicide applications will be needed to ensure season-long weed control.