Different biological, chemical and cultural treatments were used to evaluate their effects on Phymatotrichum root rot on cotton. The test site chosen for field experiment had a history of severe infestation of the fungus Pyhmatotrichum omnivorm. Urea used as a source of nitrogen fertilizer appeared to influence incidence of root rot as compared to ammonium sulfate and calcium nitrate. Florida Iron in combination with stem drenched Zn and Fe had a significant effect on suppressing the severity of cotton root rot. Generally, in-row treatment of seeds with bioculture at planting resulted in higher lint yields and less plant mortalities. Certain biological treatments in combination with chemical treatments indicate possible increase in lint yields and reduction in plant mortalities from root rot.

Cultural treatments such as crop rotation, and moldboard tillage had some effect on suppressing the disease. Data indicated that combination of different treatments along with a resistant variety may be beneficial in reducing the losses caused by root rot.