Histamine Metabolite in Urine of Subjects Exposed to Histamine and Cotton Dust

M.C. Battigelli, M.C. Madden and K. Steinsberger


The controlled exposure of normal and asthmatic subjects to histamine and card-room cotton dust causes a measurable increase in the urinary output of methyli midazole acetic acid (MIAA). Two hour collection samples obtained immediately before and following these exposures indicate that MIAA may provide a sensitive and independent indicator of exposure in fasting individuals whether histamine is inhaled or released by these challenges.

Reprinted from Proceedings of the 1983 Beltwide Cotton Dust Conference pg. 15
©National Cotton Council, Memphis TN

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Document last modified Sunday, Dec 6 1998