Field experiments were conducted in 1983 and 1984 at the Delta Branch Experiment Station to evaluate hemp sesbania (Sesbania exaltata (Raf.) Rydb. ex. A.W. Hill) control programs in cotton (Gossypium hirsutum L.). Various preemergence and directed postemergence herbicides were evaluated. Treatments were arranged in a randomized complete block design with four replications. All applications were made in water at 187 1/ha with a tractor mounted spray system. Fluometuron at 1.68 kg/ha resulted in greater suppression of hemp sesbania as a preemergence herbicide than norflurazon at 1.68 kg/ha. Neither herbicide was sufficient for acceptable season long control without a directed postemergence herbicide application. Greater than 90% control was obtained three weeks after postemergence application with cyanazine (0.67 kg/ha), prometryn (0.58 kg/ha), linuron (1.12 kg/ha), oxyfluorfen (0.28 kg/ha) and lactofen (0.22 kg/ha) when applied to 2 to 7 cm tall hem sesbania. Control was significantly reduced when applied to sesbania greater than 7 cm tall. Application of glyphosate, acifluorfen or propanil in a 1 to 3 herbicide in water solution through a rope wick did not result in adequate control of 1 to 2 meter tall sesbania.