Clomazone (Command) has not been widely utilized in Georgia cotton. Questions have been raised by industry about the potential fit for Command in Georgia cotton. With this in mind, we initiated a replicated field experiment examining a factorial arrangement of three in-furrow insecticide treatment options with 10 herbicide treatment options. The in-furrow insecticide treatment options included 1) Temik 15G at 0.75 lb ai/ac, 2) Temik (0.375) + Disyston 15G (0.5), and 3) Disyston 15G (1.0). Herbicide options included 1) Treflan (0.75) PPI (the only incorporated herbicide in this study, all other herbicides were applied PRE), 2) Command (0.75), 3) Treflan+Command, 4) Command+ Cotoran (1.5), 5) Treflan+Cotoran, 6) Command+Karmex (1.0), 7) Command+Cotoran+Reflex (0.25), 8) Treflan+Command+Cotoran, 9) Treflan+Zorial (1.5) +Cotoran, and 10) an untreated check. Weed species evaluated included a mixture of Texas panicum, entireleaf and pitted morningglory, sicklepod, and yellow nutsedge. Crop injury was negligible with all in-furrow insecticide treatments. The normal severe injury to cotton treated with Command without an in-furrow application of Disyston was not seen. Injury was less than 5% with all treatments. Weed control did not differ with in-furrow insecticide application, consequently weed control data was averaged. Reflex systems controlled yellow nutsedge 74%. Sicklepod control was equivalent (70%) with Cotoran+Zorial or Cotoran+Command mixtures. Command+Cotoran mixtures controlled morningglories 88% compared to 79% for Zorial+ Cotoran mixtures (statistically the same). Command did not adequately control Texas panicum (55%) or bristly starbur (16%). Treflan was required for adequate Texas panicum control (95%) and Cotoran controlled bristly starbur (93%).