The study of predicting the several properties of cotton knitted fabric by using statistical methods is presented. Four fabric characteristics (Fabric Weight, Ball Burst Strength of Fabric, Width Shrinkage of Fabric, Length Shrinkage of Fabric) were related to seven cotton fibers varieties, yarns, or knitting parameters selected (Twist Multiplier or Twist Factor, Yarn Count, Yarn Strength, Stitch Length, Course Density, Wale Density, Tightness Factor). On the basis of the experiment data, mathematical models were constructed with the use of multivariate analysis. The objective is trying to treat knitted fabric as an engineering material that meets special physical or dimensional requirement by adjusting the specified knitting parameters. The differences between different processing states were inspected, too.