The effects of foliar applied methanol on Upland cotton were measured in a large field study in Phoenix, AZ. An untreated check was compared to weekly applications of 30% methanol, 30% methanol plus 1% Urea and 0.1% Fe EDTA, and 1% Urea and 0.1% Fe EDTA. Plant growth and development, photosynthesis, transpiration, soil water use and lint yields were measured. There were no differences in any of the measured variables between treatments.