Tarnished plant bug, Lygus lineolaris (Palisot de Beauvois), adults were collected from cotton in one area of the Mississippi Delta near Schlater, MS, and tested for resistance to pyrethroid insecticides using a glass vial bioassay. The resistance to permethrin found in the plant bugs from Schlater was 54 times higher than permethrin resistance found in adults collected from weeds growing near cotton fields at Stoneville, MS. Adults from cotton at Schlater were also 35 times more resistant to bifenthrin than adult plant bugs collected at Stoneville. Mortality was only 7.6% for Schlater adults caged on cotton that had been treated on a spray table with Pounce (permethrin) at 0.1 lb [AI]/acre. These results show that at this rate permethrin would not control plant bugs in the cotton field at Schlater. It is not known how widespread pyrethroid resistance is in tarnished plant bugs in the Mississippi Delta, but this needs to be determined because of its effect on mid- to late-season control of this pest in cotton.