Cellcap® Bioencapsulation System: The Use of Genetic Engineering for Enhancement of Bacillus thuringiensis Toxins Against Cotton Insect Pests

Kendrick Uyeda, Carol Booth, Mikki Walz and Greg Bradfisch


The CellCap® bioencapsulation system utilizes genetic engineering to address limitations associated with Bacillus thuringiensis (Bt). With bioencapsulation, the bacteria, Pseudomonas fluorescens (Pf) encapsulates and delivers a genetically engineered Bt toxin to insect pests. Unlike native Bt strains which express multiple toxins, CellCap bioinsecticides contain a single toxin. The advantage of this system is that the most efficacious single toxin can be selected and expressed at high levels. For example, MVP® bioinsecticide contains the CryIA(c) toxin, the most active Bt toxin against budworm and bollworm pests of cotton. Encapsulation of Bt within the Pf provides greater residual control. Bioencapsulation and use of optimal toxins lead to greater consistency when compared to conventional Bt insecticides.

Reprinted from Proceedings of the 1994 Beltwide Cotton Conferences pp. 1159 - 1160
©National Cotton Council, Memphis TN

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Document last modified Sunday, Dec 6 1998