A commercial field study was conducted to demonstrate the applicability of Phaser^®/endosulfan to an Integrated Pest Management System (IPMS) on cotton in the Brazos River Valley of Texas, U.S.A.. Phaser^® was used for controlling boll weevils at low rates on an as-needed basis based on economic thresholds. Season-long scouting and sampling for pest and beneficial arthropods was conducted to collect data in the IPMS field and a field using traditional practices for insect control. The Phaser^® IPMS resulted in lower pest infestations, higher beneficial arthropod populations, less fruit damage, and yields comparable to the traditional practices of using broad-spectrum insecticides. The Phaser^® IPMS field provided a significantly higher economic profit than the traditional practices.