Two susceptible cotton (Gossypium Hirsutum L.) cultivars (DES 119 and DPL 50) and two advanced breeding lines (ST 69132 and LA 850082) moderately resistant to tobacco budworm (TBW) Heliothis virescens (F.) were grown under two management conditions in 1991 and 1992 using Bacillus thuringiensis (Bt) (once or twice weekly) and compared with a full control (FC) management condition using a pyrethroid for control of TBW. Bt plots were infested with TBW neonates (30-36/row m) once/week for six weeks beginning at pinhead square. Pyrethroid treatments were applied once/week. During the 1991 year, the moderately resistant cotton LA 850082 yielded as much lint in the Bt twice a week management condition as in the FC treatment condition. In both years, the LA 850082 suffered significantly less damage and produced more lint than the other cotton lines in virtually every management situation. Although the data varies, there appear to be no yield differences in applying one or two foliar applications of Bt a week on either of the cotton lines. There were no differences in eggs in terminals among the cotton lines but LA 850082 did have less larvae in terminals, larvae in squares, square damage, and boll damage. Growing a moderately resistant cotton like the frego bract, nectariless LA 850082 under Bt protection seems to be a promising alternative management strategy.