A strain of an insect specific fungus, Beauveria bassiana (Balsamo) Vuillemin, FTCC 74040, formulated as Naturalis-L, was effective for season long control of insects in cotton, including the boll weevil, cotton fleahopper and sweetpotato whitefly. The fungus was evaluated for full season control of insects and for early season control in combination with insecticides (bifenthrin and acephate). Aerial and ground application methods were evaluated for efficacy. Data on plant characteristics, insect damage, and lint yields are presented herein for the treatments and the application technologies.