I would like to begin by acknowledging my co-investigators: Dr. John Lefante, Dr. Robert Jones, Dr. Roy Rando and Dr. Hans Weill. This work was funded by the National Heart Lung and Blood Institute, and conducted at the Section of Bioenvironmental Research of the Tulane University School of Medicine. This discussion will include a review of: 1) the results of a previously published paper entitled "Exposure-related Declines in the Lung Function of Cotton Textile Workers: Relationship to Current Workplace Standards" (AM REV RESPIR DIS 1991; 144:675683); and 2) the results of additional analyses including the effect of both across-shift change and exposure on annual change in lung function.