DPX-PE350 represents a new family of chemistry which inhibits the enzyme acetolactate synthase. It is not a sulfonylurea or imidazolinone. DPX-PE350 is a highly active cotton herbicide candidate characterized by low use rates with a rate range of 0.25 to 1.50 ounces active per acre. Preliminary rat studies indicate the herbicide has low acute oral and dermal toxicity. This herbicide has demonstrated excellent cotton tolerance postemergence and good tolerance preemergence. DPX-PE350 is rapidly taken up by both roots and foliage. After entering the plant, the herbicides acts to inhibit cell division and growth. Studies to date indicate no yield reductions or maturity delays.

The proposed common name for DPX-PE350 is sodium salt of pyrithiobac. The chemical name is sodium 2-chloro-6-(4,5-dimethoxy-pyrimidin-2-ylthio) benzoate. Degradation in the environment occurs primarily by way of microbial and photochemical degradation.

The trade name for this experimental cotton herbicide will be "Staple".

Postemergence applications of rate range of 0.75 to 1.25 ounces resulted in control of morningglory species, prickly sida, cocklebur, velvetleaf, devils claw, hairy nightshade and pigweed.

"Staple" has demonstrated preemergence activity on morningglory species, prickly sida, velvetleaf, lanceleaf sage and pigweed.