Chemical approaches to insect control have been essential in crop production for decades. However, the development of pesticide resistance by important insect species, the rising costs of pesticides, and increasing concern for the environmental impact of chemical pesticide use has sparked greater interest, investment, and research into alternative approaches to insect control. Such an alternative is represented by Naturalis(TM) L, a biorational insecticide produced by Fermone Corporation of Phoenix, Arizona. Naturalis(TM) L, a mycoinsecticide containing an entomopathogenic fungus, has been evaluated in the laboratory, in the greenhouse and under field conditions for four years by Dr. James E. Wright at the USDA Subtropical Agricultural Research Laboratory at Weslaco, Texas. This work was performed under the Cooperative Research and Development Agreement program of the United States Department of Agriculture. Naturalis(TM) L is a formulated product based upon a naturally-occurring fungal strain of Beauveria bassiana. The product has demonstrated significant efficacy against boll weevil, cotton fleahopper and whitefly. Naturalis(TM) L is a significant breakthrough in technology since it is the first biorational product which, when applied alone, can control boll weevil. Applied by itself, or in combination with other biorational or traditional insecticides, the product can make a significant contribution to Integrated Pest Management (IPM) programs for control of boll weevil, cotton fleahopper and whitefly.