Field tests conducted at Stoneville, MS, in 1989 were designed to select the best combination of treatments for pitted morningglory control in cotton using commercially available herbicides applied to the soil and directed to the foliage. Among the four soil applied herbicides used alone (Cotoran^®, Prowl^®, Treflan^®, and Zorial^®), none gave satisfactory control, but Cotoran was significantly better than the others on the July 20 rating. The three way combination with Treflan, Cotoran, and Zorial was no better than Cotoran + Zorial. The most cost effective choices seemed to be either Cotoran alone at $8.22/A or Treflan in combination with either Cotoran or Zorial at a cost of about $13/A. All postemergence directed treatments gave good to excellent control, and the choice of herbicides did not appear crucial. Rainfall and other environmental conditions were favorable for excellent herbicide efficacy, and levels of morningglory control were higher than would normally be expected.