F₂ populations of upland cotton (Gossypium hirsutum L.) are being bred for commercial production. The potential of F₂'s of Pima cotton (G. barbadense L.) has not been investigated. The present study was conducted to determine yield potential, boll and fiber properties, and yarn strength's of a group of F₂'s at low (below 750 m) and high (above 750 m) elevation environments in the Pima belt. Lint yield of 15 F₂ populations ranged from 86 to 108% of Pima S-6 over three environments, with three F₂'s yielding significantly above PS-6. No F₂ yielded significantly above midparent or high parent values but other parent combinations may give significant increase. A significant F₂ X environment interaction for yield obtained; however, certain F₂'s were superior in yield across environments as indicated by their stability in ranking. The two highest yielding F₂'s also had longer stronger, and finer fiber with greater 22 count yarn strength compared with Pima S-6. These results indicate that F₂ populations of Pima cotton warrant further investigation for enhancing yield potential and efficient production practices in the Pima belt.