The Texas High Plains typically produces 18-20% of the U.S. and 2-4% of the world's cotton lint annually. Of the 3 million cotton producing acres, half are infested with the root-knot nematode, Meloidogyne incognita (1). The root-knot nematode attacks cotton roots and alters the host morphologically and physiologically, oftentimes making the plant more susceptible to fungal diseases. On average, root-knot nematodes are responsible for lowering lint quality and decreasing lint yield by 25% (1). Unfortunately, most of the infested cotton acreage is also dependent upon rainfall for adequate moisture. Many producers use various skip-row planting patterns to conserve this limited water supply. Our objective is to develop an optimum plant/fallow system which will allow cotton producers to help conserve soil moisture and reduce nematode populations with no increase in production costs.