Remote sensing technology was employed extensively in a regional cotton stalk destruction program directed against boll weevil, Anthonomus grandis Boheman, in the Lower Rio Grande alley of Texas. Aerial color infrared photography provided a means to determine the distribution and abundance of undestroyed cotton, which greatly facilitated regulatory activities (i.e., enhanced enforcement of stalk destruction regulations mandated under the Texas Pink Bollworm Quarantine) and ecological research on the overwintering boll weevil population. Potential regulatory and scientific applications of remote sensing technology in regional pest management programs are discussed.