As boll weevil infestations and irrigation water availability place new constraints on cotton growers in south central Arizona it is logical to apply new adjustments to the production system. More attention to irrigation, defoliation, rainfall probabilities and earlier harvest timing can have a combination of benefits. The reduction of diapausing boll weevil populations, late season insecticide applications, irrigation water use and unfavorable cotton quality should contribute several advantages leading to more profitability for cotton growers in the area.