The effect of moisture and temperature on germination of gin-run cottonseed was evaluated. Seeds with moisture contents ranging from 7.5 to 14.5% were exposed to temperatures of 50 to 80C at 5 degree increments. As moisture content, temperature, and time of exposure Increased, germination decreased. High moisture levels compounded the effect of temperature. Temperatures of 70C or higher, however, drastically lowered viability at all moisture levels. The decline of germination as seeds of different moisture levels were exposed to given temperatures was best fitted with a parabolic curve represented by the following equation: Y = a - bX + cX2, where X represented the time of exposure.