Comparative in vitro tests indicate that flusilazole and penconazole were effective in stopping growth of Pythium ultimum and Rhizoctonia Solani at 10 µg/ml. In furrow applications of these chemicals in Houston black clay, artificially infested with one or both of the above pathogens, demonstrated their efficacy in controlling pre- and postemergence damping off of cotton. Flusilazole was more active against P. ultimum than penconazole, but the reverse was observed with R. solani. Since these two fungicides are triazole derivatives that inhibit ergosterol biosynthesis, and P. ultimum lacks ergesterol in its membranes, and p. ultimum lacks ergesterol in its membranes, it is suggested these chemicals may have another mode of action.