Bollgard II, Monsanto line DPLX-01L90-D, was compared to Bollgard and conventional cotton in Jefferson and Lincoln Counties, AR, to determine efficacy against the Heliothine complex in cotton. In both trials, Bollgard and Bollgard II significantly reduced square damage and the presence of live larvae throughout the growing season when compared to the untreated conventional variety. This increased control resulted in greater yields in Jefferson County; however, Bollgard II yields were not significantly higher in Lincoln County. Further evaluation of Bollgard II is necessary to determine its feasibility in Arkansas cotton production.