Approximately eighty percent of Mississippi’s 1.62 million acres of cotton was planted to Bt-transgenic varieties in 2001. A field survey was conducted during late season to compare performance of Bt and non-Bt varieties. Bt fields sustained less caterpillar induced boll damage, 2.08% vs 2.59%, and received significantly fewer foliar insecticide treatments for control of bollworm and tobacco budworm, 0.84 vs 2.27. Differences in number of bollworm/tobacco budworm sprays applied to Bt and non-Bt were greater in the Delta region of the state than in the Hill region, which experienced very low pressure from bollworm/tobacco budworm in 2001.