Several developments have contributed to a substantial decline in applications of broad-spectrum insecticides in cotton. The Boll Weevil Eradication Program, the numerous studies demonstrating that high retention of early squares is unnecessary, and the rapid adoption of Bollgard^® varieties that express proteins of the Cry1A(c) strain of Bacillus thuringiensis (B.t.) for control of certain lepidopterous pests. Also, Bollgard II^® varieties that afford control of most major lepidopterous pests by expressing proteins of both the Cry1A(c) and Cry2A(b) strains of B.t. will soon be available to producers. Such varieties will further diminish the need for insecticides.