The desire to cut costs and improve efficiency and accuracy was the prerequisite for initiating cotton picker conversions at Phytogen Seed Company. In this report, we describe the development of an improved and cost effective system to harvest yield plots for the two cotton breeding programs in North America. An agricultural engineer was hired to design/convert a two-row picker, creating the first, functional prototype. An additional two-row picker was converted the following year, based on the original prototype. That same year a four-row picker was designed/converted to capture greater cost-savings, efficiency, and accuracy. The four-row system was developed based on an unrelated structural design from the original two- row prototype. The four-row system allows for harvesting two plots simultaneously, yet independent of each other. The two-row system eliminates five to seven working bodies, completing the same tasks in the same amount of time with an increased level of safety and accuracy. Conversely, the four-row system eliminates five to seven working bodies, completing the same tasks nearly three fold quicker than the original plot-harvest system. The original harvest system, using a bagger- picker, is out-dated for yield plot harvest, but remains a superior system for harvesting seed increases. With the development of the two- and four-row load-cell systems, resources were shifted to harvesting seed increases with the bagger-picker rather than spending excessive time, energy, and costs on harvesting yield plots. The converted systems have increased safety, efficiency, accuracy, and cost-savings by replacing the bagger-picker function with respect to harvesting yield plots. The systems were estimated to pay for themselves within one year of operation.