Six trials were conducted during 1999-2001 to evaluate the effectiveness of Telone II against reniform nematode. Telone II was applied as a preplant fumigant at the rate of 3.0 gallons per acre. Temik 15% at 3.5-4.0 pounds per acre is the producer standard and was compared alone or in combination with the Telone. Telone II had significantly higher yields than the Temik 15%G alone in four of the six locations. The greatest differences in yield between Telone II combined with Temik 15%G and Temik 15%G alone were during 1999-2000 (difference of 347 pounds). Differences were only 39 pounds of seed cotton at the two locations tested during 2001 primarily because of boll rot injury. A rate study of Telone at three locations showed an average of 1540, 1943, 1903, and 2080 pounds of seed cotton for the 0, 1.5-1.8, 3.0, and 5.0-6.0 rates of Telone II.