Studies were conducted in Imperial Valley, CA to evaluate neonicotinoid insecticides and pyrethroid insecticides for control of silverleaf whitefly in cotton. Neonicotinoid insecticidal compounds, acetamiprid (Assail®), imidacloprid (Provado®), and thiamethoxam (Actara®) were compared to the standard whitefly insecticide fenpropathrin (Danitol®) in a tank mixture with an organophosphate, acephate (Orthene®) and compared to a cyclodiene compound endosulfan (Thiodan® or Phaser®) for control efficacy of whitefly adults, eggs and nymphs. The neonicotinoid insecticide, Assail®,and Danitol® plus Orthene® treatments provided the highest levels of control for silverleaf whitefly.