Beginning in 1995, one year before its commercial release, the economics of Bollgard cotton on the field scale have been examined by a number of investigators, including independent scientists and Monsanto. Many of these comparisons have been the results of researchers working over several years in one state or geography and have been reporting in the Proceedings of the Beltwide Cotton Conference. The results demonstrate that growers, on average, realize a significant Bollgard advantage, when using Bollgard cotton due to a combination of increased yields and decreased insect control costs. The economic advantage of Bollgard over conventional cotton production over the five-year test period in the independent trials was $49.80. This is consistent with the average advantage ($44.70) calculated for Bollgard from 485 economic comparisons sponsored by Monsanto over the period of 1995 to 2000. Data from Monsanto’s 2000 field economic comparison trials (27 sites) gave an average Bollgard advantage of approximately $36 per acre.