Transgenic cotton varieties (Bollgard® and BollgardII®) were evaluated in Stoneville, MS in 2000. It was apparent that the two protein product (BollgardII®) had increased activity against a multitude of lepidopteran pests compared to Bollgard®. Studies profiling the season-long expression of both proteins in BollgardII® indicated that the new protein (Cry2Ab) was expressed at a much higher level than Cry1Ac in Bollgard® and BollgardII®.