As with mepiquat chloride recommendations developed for Acala cotton in CA, similar types of growth regulators should be used where field history suggests high vigor problems, or when within-season plant mapping information indicates low to moderate fruit retention combined with moderate to high vigor measured as plant height or growth rates. Results indicate that mepiquat chloride types of materials can be effective in helping manage vegetative growth, but impacts on yield are smaller and less consistent than found with Acala cotton. Results also show that the potential impact of delayed irrigations in combination with growth regulator use depends to a significant extent on fruit retention.