Renewed interest of ultra narrow row production (UNR) methods for cotton (Gossypium hirsutum L.) by industry, researchers, and producers, suggests evaluation of several management components is needed in order to optimize them. Plant populations, varieties, and use of plant growth regulators are among those agronomic factors requiring further evaluation. Three field studies were conducted at the Delta Research and Extension Center in Stoneville, MS, in 1999 and 2000. In the first study, row spacings of 10-in., 15-in., and 40-in. rows and six varieties consisting of Fibermax 832, Stoneville ST 474, Stoneville BXN47, Suregrow 125BR, Paymaster 1220RR, and D&PL NuCotn35 were evaluated. A second study consisted of 10-in. and 15-in. row spacings and plant populations of 75 000 plants/A, 100 000 plants/A, 125 000 plants/A, and 150 000 plants/A. A third study evaluated 10-in., 15-in., and 30-in. row spacings and five Pix (mepiquat chloride) applications consisting of an untreated check, four applications at 4 oz/A, two applications at 8 oz/A, four applications at 8 oz/A, and four applications at 12 oz/A. Mepiquat chloride applications began at pinhead square and were applied every 7 to 10 days depending on growing conditions.