On farm split field comparisons were conducted during the 1999 and 2000 growing season to compare the agronomics and economics of Bollgard/Roundup Ready cotton to Roundup Ready cotton on the Southern High Plains of Texas. These trials were located from Lamesa to Hereford. PM 2200RR was compared to PM 2280 BGRR and PM 2326 RR was compared to PM 2326 BGRR on approximately 13 split field comparisons each year. These comparisons were conducted each year with the BGRR variety planted on one side of the field and the RR planted on the adjacent side. Each variety/technology was managed independent of the adjacent variety/technology regarding insecticide use for bollworm control. Bollgard varieties tended to be slightly shorter plants and earlier maturing. BGRR cotton demonstrated a yield increase of approximately66 lbs/acre across all varieties over both years. Total fruit retention and bolls/plant were significantly increased as a result of bollgard. Preliminary cost analysis indicates an average savings of $28.66 per acre across both varieties and two years data.