Genetically engineered cotton varieties containing the Roundup Gene® offer promise for reduced weed control inputs. However, farmer acceptance has been slow due to the narrow over-the-top application window and perceived yield losses or delayed maturity associated with in crop applications of glyphosate (Roundup) herbicide after the four leaf stage of cotton. Roundup herbicide provides no residual weed control and late germinating weeds often cause harvest problems and yield losses.